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目的 :探讨前列腺炎对血清 PSA浓度的影响。方法 :选择 48例 2 1～ 40岁的前列腺炎患者 ,用 EL ISA法测定直肠指检前的血清 PSA浓度 ,与正常组 2 1例对照 ,并对比治疗前后血清 PSA浓度的变化。结果 :前列腺炎组和对照组的血清 PSA浓度分别为 (1.5± 0 .4)和 (0 .4± 0 .2 ) μg/ L,两组间有极显著性差异 (t=11.96 ,P<0 .0 0 1) ;31例治疗有效者 ,治疗后血清 PSA浓度较治疗前明显下降 (P <0 .0 0 1) ,而 12例无效者 ,血清 PSA浓度较治疗前下降不明显 (P >0 .0 5 )。结论 :前列腺炎时血清 PSA浓度明显升高 ,但随着炎症的消失 ,PSA浓度可逐渐恢复正常。
Objective: To investigate the effect of prostatitis on serum PSA concentration. Methods: Forty-eight patients with prostatitis aged 21 to 40 years old were enrolled in this study. Serum PSA concentration before rectal examination was measured by ELISA. The changes of serum PSA levels before and after treatment were compared with those in the control group. Results: Serum PSA concentrations in prostatitis group and control group were (1.5 ± 0.4) and (0.4 ± 0.2) μg / L, respectively. There was a significant difference between the two groups (t = 11.96, P < (P <0.01). However, in the 31 patients with effective treatment, the serum PSA concentration decreased significantly after treatment (P <0.01), while 12 patients were ineffective. The serum PSA concentration was not significantly lower than before treatment (P > 0 .0 5). Conclusion: Serum PSA concentration in prostatitis increased significantly, but with the disappearance of inflammation, PSA concentration gradually returned to normal.