许多药物及候选药物完成预期体内药理学作用之前,都要经过复杂的传送过程。药品的物理化学特性决定了药物传送载体经常改变。药物的难溶性、渗透性差、相对分子质量高、化学性质不稳定及半衰期短等是制剂研究者面临的最常见挑战。越来越多的科学家及制药公司负责人都意识到药物 Many medications and drug candidates go through a complex process of delivery before they are expected to achieve the desired pharmacological effects in vivo. The physicochemical properties of the drug determine that the drug delivery vehicle often changes. Poor solubility of drugs, poor permeability, high molecular weight, chemical instability and short half-life are the most common challenges researchers face. More and more scientists and drug company executives are aware of drugs