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应用核素心室造影评价35例系统性红斑狼疮(SLE)病人亚临床心脏受累期心功能的变化。结果显示,SLE病人左室收缩功能参数如左室射血分数(LVEF)、峰射血率(PER)、前1/3射血分数(1/3EF)及峰射血时间(TPER)均无显著性改变,活动期(n=24)和非活动期病人(n=11)左室舒张功能参数如峰充盈率(PFR)、前1/3充盈分数(1/3FF)明显降低,活动期更明显。62.5％的活动期和36.4％的非活动期病人1/3FF降低(<20％)。且活动期病人左室相角程标准差(LN-SDP)增大,收缩同步性减低。活动期和非活动期病人右室功能均降低。说明SLE病人即使左室收缩功能正常也存在左室舒张功能和右室功能障碍。
Radionuclide ventriculography was used to evaluate the changes of cardiac function in 35 patients with systemic lupus erythematosus (SLE) during subclinical cardiac involvement. The results showed that left ventricular systolic function parameters such as left ventricular ejection fraction (LVEF), peak ejection rate (PER), first 1/3 ejection fraction (1 / 3EF) and peak ejection time (TPER) Significant changes in left ventricular diastolic function parameters such as peak filling rate (PFR) and first 1/3 filling fraction (1 / 3FF) in active stage (n = 24) and inactive patients (n = 11) More obvious. 62.5% of the active phase and 36.4% of inactive patients 1 / 3FF decreased (<20%). And active patients with left ventricular phase angle standard deviation (LN-SDP) increased systolic synchrony decreased. Right ventricular function was decreased in both active and inactive patients. SLE patients with left ventricular systolic function even if there is the existence of left ventricular diastolic function and right ventricular dysfunction.