由于甲状旁腺激素(PTH)、降钙素(calcitonin)、VitD的深入研究,有关钙代谢的探讨亦在迅速发展。除上述钙调节激素之外,骨钙素(osteocalcin,OC)、骨结合素(osteonectin)、破骨细胞激活因子(osteoclastactivating factor,OAF)、偶联因子(couplingfactor)等因子对骨的再塑(remodelling)亦有重要作用;已明确钙调蛋白(calmodulin)为蛋白结合钙,此物质在细胞内传导机构上有重要作用,有关钙调蛋白的研究正在深入。临床上已证明假性甲状旁腺功能低下症 Due to the in-depth study of PTH, calcitonin and VitD, the exploration of calcium metabolism is also rapidly developing. In addition to the above calcium-regulating hormones, factors such as osteocalcin (OC), osteonectin, osteoclastactivating factor (OAF), coupling factor and the like, remodeling also plays an important role; calmodulin has been identified as a calcium-binding protein that plays an important role in intracellular signaling mechanisms and the research on calmodulin is in progress. Pseudo-hypoparathyroidism has been clinically proven