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本文对近年来国内外所研究的酚苷类药物肠吸收的文献进行了检索和分析,介绍了目前常用的研究方法和模型,并对影响其肠吸收的因素进行了综述,在此基础上总结了酚苷类药物肠吸收动力学研究现状,旨在为提高其口服生物利用度、改进剂型、发现新药和临床合理使用提供参考。
In this paper, we reviewed and analyzed the literature of intestinal absorption of phenolic glycosides studied in recent years at home and abroad, introduced the commonly used research methods and models, and summarized the factors that affect their intestinal absorption, based on this summary The research status of intestinal absorption kinetics of phenolic glycosides drugs is to provide reference for improving oral bioavailability, improving dosage forms, discovering new drugs and clinical rational use.