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目的:估算n 99Tcn m-亚甲基二膦酸盐（MDP）骨显像患者对公众及核医学技师产生的照射剂量。n 方法:选取2019年9至12月于四川大学华西医院行n 99Tcn m-MDP骨显像的64例患者进行回顾性研究，其中男性38例、女性26例，年龄24~82（55.1±12.8）岁。在静脉注射n 99Tcn m-MDP 15 min后，使用核辐射监测探测仪测量距离患者1.0 m和0.3 m处的剂量当量率（DR）。根据美国国家辐射防护和测量委员会提出的人类社会活动模式和国际辐射防护委员会提出的n 99Tcn m-MDP在人体的代谢模型，计算n 99Tcn m-MDP骨显像患者对公众及核医学技师的照射剂量。n 结果:64例患者的DR（1.0 m）为15.9~32.7（22.6±3.6） μSv/h、DR（0.3 m）为70.8~154.2（105.5±20.9） μSv/h。与n 99Tcn m-MDP骨显像患者白天接触的家庭成员的照射剂量为13.3~27.4（18.9±3.0） μSv；夜间同床共寝的家庭成员的照射剂量为78.2~170.3（116.5±23.4） μSv；单位工作同事的照射剂量为17.6~36.2（25.0±4.0） μSv；邻座乘客的照射剂量为219.9~478. 8（327.5±65.7） μSv。核医学技师每接触1例n 99Tcn m-MDP骨显像患者的照射剂量为3.9~8.5（5.8±1.2） μSv。n 结论:99Tcn m-MDP骨显像患者对公众及核医学技师的照射剂量远低于相应人群的照射剂量限值。n “,”Objective:Radiation doses to the general public and nuclear medicine technicians from patients undergoing n 99Tcn m-methylenediphosphonate(MDP) bone scintigraphy were estimated.n Methods:A total of 64 patients (38 males and 26 females, aged 24-82 (55.1±12.8) years) undergoing bone scintigraphy with n 99Tcn m-MDP were retrospectively enrolled in this study. Approximately at 15 minutes after injection of n 99Tcn m-MDP, whole-body dose-equivalent rate (DR) was measured with a radiation-survey meter at 0.3 meter and 1.0 meter from the patients with nuclear radiation monitoring detector. On the basis of the human social contact model defined by the National Council on Radiation Protection and Measurements and human n 99Tcn m-MDP metabolic rate suggested by the International Commission of Radiological Protection, the radiation doses to the general public and the nuclear medicine technicians after exposure to patients undergoing n 99Tcn m-MDP bone scintigraphy were calculated.n Results:The whole-body DR values of 64 patients at 15 minutes after injection of n 99Tcn m-MDP were 70.8-154.2 (105.5 ± 20.9) and 15.9-32.7 (22.6±3.6) μSv/h, respectively, at 0.3 meter and 1.0 meter. The following radiation doses were estimated: to a family member contacting with a patient at daytime 13.3-27.4 (18.9±3.0) μSv; to a family member sleeping with a patient at night 78.2-170.3 (116.5±23.4) μSv, to a colleague 17.6-36.2 (25.0±4.0) μSv and to a adjacent passenger 219.9-478.8 (327.5±65.7) μSv. The radiation dose to a technician per n 99Tcn m-MDP imaging patient was estimated to be 3.9-8.5 (5.8±1.2) μSv.n Conclusion:The predicted radiation doses to the general public and technicians from exposure to patients undergoing n 99Tcn m-MDP bone scintigraphy are significantly lower than the regulatory dose limits.n