脑胶质瘤是最常见的原发性颅内肿瘤,约占颅内肿瘤的46%。传统治疗,手术难以全切;化疗和放疗既不能高度特异性地杀伤胶质瘤细胞,又可能产生中枢神经系统的毒、副作用。胶质瘤是神经外科领域难治性疾病,目前对于胶质瘤的治疗仍无突破性进展,且对其发生、发展机制缺乏认识。因此阐明其发病机理、寻找新的治疗手段对于解决胶质瘤 Glioma is the most common primary intracranial tumor, accounting for 46% of intracranial tumors. Traditional treatment, surgery is difficult to cut; chemotherapy and radiotherapy neither highly specific killing of glioma cells, but also may produce central nervous system toxicity and side effects. Glioma is a refractory disease in the field of neurosurgery. At present, there are still no breakthroughs in the treatment of gliomas, and there is a lack of understanding of its occurrence and development mechanism. Therefore, elucidate the pathogenesis and find new treatments for glioma