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[目的]综合评价微生态制剂治疗成人功能性便秘(FC)中的临床效果。[方法]82例FC患者随机分为2组,对照组40例,治疗组42例。所有病例均嘱其改善不良生活习惯;对照组给予乳果糖溶液联合莫沙比利口服;治疗组在对照组治疗基础上加服双岐四联活菌片。观察治疗2周及治疗结束后3个月的临床疗效。[结果]治疗2周后,治疗组的总有效率明显高于对照组(P<0.01);停止治疗3个月时,治疗组的总有效率、显效率均高于对照组(P<0.01)。[结论]微生态制剂在FC的治疗中有良好的协同、增效作用,有利于疗效的巩固和维持。
[Objective] To evaluate the clinical efficacy of probiotics in the treatment of adult functional constipation (FC). [Methods] 82 patients with FC were randomly divided into two groups, the control group of 40 cases, the treatment group of 42 cases. All cases were instructed to improve their bad habits; the control group was given lactosucrose solution combined with mosapride oral; treatment group in the control group based on the treatment plus service Bifidobacterium quadriceps. Observe the clinical efficacy of 2 weeks after treatment and 3 months after the end of treatment. [Results] After 2 weeks of treatment, the total effective rate of the treatment group was significantly higher than that of the control group (P <0.01). The total effective rate and effective rate of the treatment group were significantly higher than those of the control group ). [Conclusion] There is a good synergistic and synergistic effect of probiotics in the treatment of FC, which is beneficial to the consolidation and maintenance of therapeutic effects.