Shirasska报道,带瘤小鼠脾脏DNA的合成及含量明显增高,相当于对照组的两倍左右,认为肿瘤组织可以释放生长刺激因子,增强宿主组织器官DNA的合成;但也有不少学者认为肿瘤组织释放的是生长抑制因子,能抑制淋巴细胞的增殖。我们在以前的试验中已经发现,在肿瘤早期,ICR带瘤鼠胸腺发生萎缩,胸腺细胞减少,但胸腺细胞的有丝分裂反而升高,脾脏肿大,外周免疫器官和外周血中的T淋巴细胞增多;但到了肿瘤晚期,胸腺 Shirasska reported that the synthesis and content of spleen DNA in tumor-bearing mice was significantly higher than that in the control group. It is believed that tumor tissues can release growth stimulatory factors and enhance DNA synthesis of host tissues and organs; however, many scholars believe that tumor tissue The release of growth inhibitory factors can inhibit lymphocyte proliferation. In our previous experiments, we have found that in the early stage of tumors, the thymus of ICR mice with tumors shrinks and the number of thymocytes decreases. However, the mitochondria of thymocytes increase, the spleen enlarges, and peripheral T lymphocytes increase in peripheral immune organs and peripheral blood. But by the end of the tumor, the thymus