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目的总结卵巢早衰的临床资料,探讨卵巢早衰的治疗。方法对24例卵巢早衰患者的临床资料进行回顾性分析。结果本组24例患者中,有生育要求4例,随访至今尚无1例妊娠。其余20例患者经治疗后,治愈3例(12.5%),有效11例(45.83%),无效8例(33.3%)。总有效率为58.33%。人工周期治疗半年后复查血清FSH、LH、E2水平有效组FSH及LH均较前下降,FSH较治疗前明显下降。E2前后差异无统计学意义。结论卵巢早衰是一种多因素引起的疾病,治疗困难,需要重视和研究。
Objective To summarize the clinical data of premature ovarian failure and to explore the treatment of premature ovarian failure. Methods The clinical data of 24 patients with premature ovarian failure were retrospectively analyzed. Results In this group of 24 patients, there are 4 cases of reproductive requirements, no one has been followed up until pregnancy. The remaining 20 patients after treatment, cured in 3 cases (12.5%), effective in 11 cases (45.83%), ineffective in 8 cases (33.3%). The total effective rate is 58.33%. The serum FSH, LH, and E2 levels in the effective group after the artificial cycle treatment for 6 months were lower than those in the effective group, and the FSH was significantly lower than that before treatment. E2 before and after the difference was not statistically significant. Conclusions Premature ovarian failure is a multifactorial disease that is difficult to treat and needs attention and research.