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本文对１５０例肝炎后肝硬化（ＣＩＲ）患者的血清标本回顾性地检测了ＨＢＶ、ＨＣＶ及ＨＤＶ感染标志，结果ＨＢＶ感染率为１００％，ＨＣＶ感染率为３９．３％，ＨＤＶ感染率为４２．０％，有６２．７％ＣＩＲ患者重重叠感染了二种以上肝炎病毒。其中二重感染率：ＨＢＶ／ＨＣＶ２０．７％，ＨＢＶ／ＨＤＶ２３．３％，三重感染率为１８．７％，均显著高于慢性乙型肝炎患者（Ｐ＜０．０１或Ｐ＜０．０５）。结果提示，ＨＢＶ、ＨＣＶ和ＨＤＶ感染与肝硬化的发生关系密切，肝炎病毒重叠感染可能导致肝病加重。
In this paper, we retrospectively detected the markers of HBV, HCV and HDV in serum of 150 patients with posthepatitic cirrhosis (CIR). The results showed that the HBV infection rate was 100%, the HCV infection rate was 39.3% and the HDV infection rate was 42 .0%, 62.7% of CIR patients were heavily infected with two or more hepatitis viruses. Among them, the rates of double infection were: HBV / HCV20.7%, HBV / HDV23.3%, triple infection rate was18.7%, which were significantly higher than those in patients with chronic hepatitis B (P <0.01 or P <0.05 ). The results suggest that the infection of HBV, HCV and HDV is closely related to the occurrence of cirrhosis. Over-infection of hepatitis B virus may result in increased liver disease.