论文部分内容阅读
目的探索人群华支睾吸虫病不同流行程度地区的防治化疗措施。方法选择广东省人群华支睾吸虫病高、中、低度流行区,分别设立干预组和对照组,干预组分别对3岁以上人群、重点人群和感染者实施阿苯达唑驱虫干预措施;对照组不采取任何措施。结果干预1年后,干预组人群华支睾吸虫感染率显著降低,高、中度和低度流行区分别下降了47.90%、86.52%和100%;肝脏B超异常率分别下降了26.50%、31.00%和100%;丙氨酸氨基转移酶异常率分别下降了48.70%、62.30%和100%,天冬氨酸氨基转移酶异常率分别下降了55.50%、39.90%和100%。对照组人群所有指标无下降趋势。结论人群华支睾吸虫病不同流行程度地区应采取不同的化疗措施。
Objective To explore the prevention and treatment of clonorchiasis in different epidemic areas of population. Methods The epidemic areas of high, medium and low levels of Clonorchis sinensis in Guangdong population were selected and divided into intervention group and control group respectively. The intervention group were given the detoxification of albendazole against the population above 3 years old, the key population and the infected persons The control group did not take any measures. Results After 1 year of intervention, the infection rate of Clonorchis sinensis in the intervention group was significantly decreased, while the prevalence in the high, moderate and low endemic areas decreased by 47.90%, 86.52% and 100% respectively; the abnormal rate of liver B-ultrasound decreased by 26.50% 31.00% and 100% respectively. The abnormal rates of alanine aminotransferase decreased by 48.70%, 62.30% and 100%, while the abnormal rates of aspartate aminotransferase decreased by 55.50%, 39.90% and 100% respectively. The control group of all the indicators no downward trend. Conclusions Clonorchis sinensis should be treated with different chemotherapeutic drugs in different epidemic areas.