帕金森病(Parkinson’s Disease,PD)是中枢神经系统退行性疾病之一。运动症状有静止性震颤、肌强直、运动迟缓、姿势平衡异常,是PD诊断的主要依据~([1])。非运动症状主要包括神经心理障碍(抑郁、焦虑、认知障碍、注意力缺乏、淡漠等)、自主功能障碍(直立性低血压、便秘、心悸、多汗、膀胱功能障碍等)、感觉异常(疼痛、嗅觉障碍、视觉障碍等)、睡眠障 Parkinson’s Disease (PD) is one of the central nervous system degenerative diseases. Motor symptoms of rest tremor, muscle rigidity, bradykinesia, posture balance anomalies, is the main basis for the diagnosis of PD ~ ([1]). Non-motor symptoms include neuropsychological disorders (depression, anxiety, cognitive impairment, attention deficit, indifference, etc.), autonomic dysfunction (orthostatic hypotension, constipation, palpitations, hyperhidrosis, bladder dysfunction, etc.) Pain, olfactory disorders, visual disturbances, etc.), sleep disorders