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目的探讨结直肠癌根治术后转移复发的相关因素。方法 2001年1月—2007年1月结直肠癌根治病例455例进行转移复发病例观察及进行相关因素观察。结果 455例结直肠癌根治后进行随访3~5年,转移、复发116例,转移复发率25.49%;肿瘤情况、肿瘤病理、辅助放化疗方面因素比较,P<0.05,有显著差异性。结论结直肠癌术后转移、复发相关因素进行分析筛选出具备高危复发转移因素的结直肠癌患者,仔细认真的对待,应注意术中无瘤操作、术后辅助放化疗等。强调首次手术的重要性,严格掌握手术适应证,提高医生对结直肠癌复发、转移规律的认识,制定合理的治疗方案,规范手术操作,降低术后转移和复发。
Objective To investigate the related factors of metastasis and recurrence after radical resection of colorectal cancer. Methods From January 2001 to January 2007, 455 patients with radical resection of colorectal cancer underwent metastatic recurrence and observed the related factors. Results A total of 455 cases of colorectal cancer were followed up for 3 to 5 years. Metastasis and recurrence occurred in 116 cases. The metastasis and recurrence rate was 25.49%. The tumor condition, tumor pathology, and adjuvant radiotherapy and chemotherapy factors were compared, P<0.05. There was significant difference. Conclusions The factors related to metastasis and recurrence after colorectal cancer surgery were analyzed to screen out colorectal cancer patients with high-risk recurrence and metastasis factors. Careful treatment should be performed. Attention should be paid to intraoperative tumor-free operation, postoperative adjuvant radiotherapy and chemotherapy. Emphasize the importance of the first operation, strictly grasp the surgical indications, improve the doctor’s knowledge of the recurrence and metastasis of colorectal cancer, formulate a reasonable treatment plan, standardize the operation, and reduce the postoperative metastasis and recurrence.