维生素B_6合成方法近十年来的进展

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維生素B_6类包括三个化合物:吡哆醇(pyridoxine,I)、吡哆醛(pyridoxal,Ⅱ)及吡哆胺(pyridoxamine,Ⅲ)。通常所称的維生素B_6仅系指吡哆醇。吡哆醇在体內为蛋白貭正常代謝所必需,它的重要性可与維生素B_1对碳水化合物代謝的关系相比。吡哆醇在体內的生理效用是通过它的醛及胺的化合物发揮的,吡哆醛在体內組成脫羧輔酶,促使氨基酸在体內的脫羧作用。吡哆胺則組成氨基轉換輔酶,起着氨基酸与α-酮酸之間氨基的轉换作用。 Vitamin B_6 includes three compounds: pyridoxine (I), pyridoxal (Ⅱ) and pyridoxamine (Ⅲ). Commonly referred to as vitamin B_6 only refers to pyridoxine. Pyridoxine is required for the normal metabolism of protein 在 in the body and its importance can be compared with the relationship of vitamin B 1 to carbohydrate metabolism. The physiologic utility of pyridoxine in the body is exerted by its aldehyde and amine compounds, which form decarboxylated coenzymes in the body and promote the decarboxylation of amino acids in the body. Pyridoxamine is composed of amino-conversion coenzyme, amino acids and amino acids play a role in the conversion between.
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