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目的探讨固尔苏联合经鼻持续气道正压通气(NCPAP)治疗新生儿呼吸窘迫综合征(NRDS)的疗效及其对血气指标的影响。方法选取2012年6月-2013年6月该院收治的NRDS患儿68例为研究对象,随机分为观察组和对照组,每组各34例。对照组采用固尔苏联合机械通气治疗,观察组采用固尔苏联合NCPAP治疗。观察两组患儿治疗效果、血气指标变化及并发症情况。结果观察组治愈率、Pa O2、Sa O2水平均明显高于对照组,住院时间、吸氧时间、Pa CO2水平和并发症发生率明显低于对照组,差异均有统计学意义(P<0.05)。结论固尔苏联合NCPAP有利于改善NRDS患儿血气指标,降低肺部并发症,提高治疗效果。
Objective To investigate the curative effect and clinical effect of Gul-Su-Su combined with nasal continuous positive airway pressure (NCPAP) on neonatal respiratory distress syndrome (NRDS). Methods Sixty-eight children with NRDS admitted to our hospital from June 2012 to June 2013 were randomly divided into observation group and control group, 34 cases in each group. The control group was treated with Cure and Soviet Union mechanical ventilation, and the observation group was treated with Cure and Soviet Union combined with NCPAP. The therapeutic effect, changes of blood gas index and complications in both groups were observed. Results The cure rate, Pa O2, Sa O2 levels in observation group were significantly higher than those in control group. The length of hospital stay, oxygen inhalation time, Pa CO2 level and complication rate were significantly lower than those in control group (P <0.05 ). Conclusion Gastrodia combined with NCPAP is beneficial to improve the blood gas index of NRDS children, reduce pulmonary complications and improve the therapeutic effect.