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目的:探讨硝苯地平联合硫酸镁治疗重度子痫前期的疗效。方法:将2015年1月-2016年12月我院收治重度子痫前期的80例孕妇随机分为对照组和研究组,对照组采用硫酸镁治疗,研究组在对照组基础上加用硝苯地平治疗,比较两组患者的临床疗效。结果:研究组患者的收缩压和舒张压与治疗前相比(P<0.05),具有统计学差异。对照组和研究组治疗总有效率分别为90.0%和97.5%,后者高于前者(P>0.05),但无统计学差异。不良妊娠包括早产、产后出血、新生儿窒息和宫内窘迫,对照组和研究组产妇总不良妊娠发生率分别为22.5%和5.0%,前者显著高于后者(P<0.05),具有统计学差异。结论:硝苯地平联合硫酸镁可有效治疗重度子痫前期产妇,能够有效改善患者临床症状,控制产妇血压。
Objective: To investigate the efficacy of nifedipine combined with magnesium sulfate in the treatment of severe preeclampsia. Methods: From January 2015 to December 2016, 80 pregnant women with severe preeclampsia in our hospital were randomly divided into control group and study group. The control group was treated with magnesium sulfate. The study group was treated with nbenzene Territory treatment, the clinical efficacy of two groups were compared. Results: The systolic and diastolic blood pressures in the study group were significantly different from those before treatment (P <0.05). The total effective rates of the control group and the study group were 90.0% and 97.5% respectively, which were higher than the former (P> 0.05), but there was no significant difference. The incidences of adverse pregnancy including prematurity, postpartum hemorrhage, neonatal asphyxia and intrauterine distress were 22.5% and 5.0% respectively in the control group and the study group, the former was significantly higher than the latter (P <0.05) difference. Conclusion: Nifedipine combined with magnesium sulfate can effectively treat severe preeclampsia mothers, which can effectively improve the clinical symptoms and control maternal blood pressure.