传统的营养支持疗法常偏重于三大营养素的补充,而ICU中危重患儿可能面临着微量元素的缺乏、分布异常或利用障碍,但往往为人们所忽视。现就危重患儿可能存在的其余5种微量元素的代谢紊乱进行探讨,着重讨论在危重疾病的应激状态下,微量元素的代谢变化、临床表现、检测方法及具体补充方案。 Traditional nutritional supportive therapy often emphasizes the supplement of the three major nutrients, and critically ill children in the ICU may face the lack of trace elements, abnormal distribution or utilization disorders, but often overlooked by people. Metabolic disorders of the remaining five kinds of trace elements may exist in critically ill children, with emphasis on the metabolic changes of trace elements, clinical manifestations, detection methods and specific programs of supplementation in critically ill conditions.