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作者利用高效液相色谱法测定８名健康自愿受试者交叉口服对乙酰氨基酚滴剂和片剂１０００ｍｇ以后，血浆中对乙酰氨基酚的浓度，所得药－时曲线均符合二室模型。平均达峰时间分别是０．８６±０．０８和１．４８±０．３９ｈ，平均血浆药物峰浓度分别是１１．２３±０；９３和８．７９±０．９３ｍｇ／Ｌ平均消除半衰期分别为３．０３±０．７９和２．５１±１．１０ｈ，平均曲线下面积分别为４２．３５±６．２０和４０．６０±６．７９ｍｇ／Ｌ·ｈ，以片剂的ＡＵＣ为１００％，口服滴剂的相对生物利用度为１０５．５８％。结果表明：这两种制剂在人体内具有生物等效性。
The authors used HPLC to determine the concentration of paracetamol in plasma following oral administration of paracetamol drops and tablets at a dose of 1000 mg in eight healthy volunteers. The resulting pharmacokinetic-time curves fit a two-compartment model. The mean time to peak reached 0.86 ± 0.08 and 1.48 ± 0.39 h, respectively. The mean peak plasma concentrations were 11.23 ± 0.93 and 8.79 ± 0.93 mg / L, respectively. The mean elimination half-life Respectively 3.03 ± 0.79 and 2.51 ± 1.10h, the average area under the curve were 42.35 ± 6.20 and 40.60 ± 6.79mg / L · h, respectively. The AUC of the tablets was 100%, the relative bioavailability of oral drops was 105.58%. The results show that both formulations are bioequivalent in humans.