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目的探讨腺苷负荷心肌核素显像对于冠状动脉介入治疗的临床意义。方法冠心病可疑患者住院,行腺苷负荷心肌核素显像和冠状动脉造影,根据需要进行介入治疗,介入治疗后3~7天复查腺苷负荷心肌核素显像。腺苷负荷心肌核素显像采用单光子发射断层显像图像采集系统,腺苷总量为840ΜG/KG,6分钟匀速静脉泵入,腺苷泵入3分钟时静脉推注99MTC-MIBI925MBQ,1·5小时后进行心肌断层显像。若异常,次日行静息心肌显像。核素显像左室心肌分为17个节段,心肌灌注分4级。结果63例冠心病患者,平均(63±10)岁,40例得到介入处理,其中28例患者冠状动脉介入处理后复查腺苷负荷心肌核素显像,介入后心肌核素血流灌注较介入前明显改善(P<0·01)。结论腺苷负荷心肌核素显像对于冠心病患者冠状动脉介入前病变分析以及介入后疗效判断有一定的临床意义。
Objective To investigate the clinical significance of adenosine stress myocardial imaging for coronary intervention. Methods Suspected coronary heart disease patients were hospitalized adenosine stress myocardial imaging and coronary angiography, according to the need for interventional treatment, 3 to 7 days after interventional treatment of adenosine stress myocardial nuclear imaging review. Adenosine load myocardial imaging using single photon emission tomography image acquisition system, adenosine total 840MG / KG, 6-minute intravenous infusion of constant, adenosine 3-minute intravenous injection of 99MTC-MIBI925MBQ, 1 Myocardial tomography was performed 5 hours later. If abnormal, resting myocardial imaging next day. Radionuclide imaging of left ventricular myocardium is divided into 17 segments, myocardial perfusion points 4. Results 63 patients with coronary heart disease (63 ± 10) years old, 40 cases were involved in the intervention, including 28 patients after coronary intervention after adenosine stress myocardial nuclear imaging review after interventional myocardial nuclide perfusion than the intervention Before significant improvement (P <0.01). Conclusions Adenosine load myocardial imaging for coronary heart disease in coronary artery lesions before PCI analysis and to determine the efficacy of intervention has some clinical significance.