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蛋白激酶C(PKC)是一种依赖于磷脂和Ca~(2+)的蛋白激酶,在生物界中广泛存在,并分布在哺乳动物的各种组织中。在信号传导过程中,磷脂肌醇系统最终以活化PKC和Ca~(2+)动员的方式完成胞外信息的传递。由于磷脂肌醇系统介导的胞外信号之广,因而PKC与诸如受体的增效和脱敏等生理过程以及细胞分化增殖,
Protein kinase C (PKC) is a protein kinase that is dependent on phospholipids and Ca 2+ . It is widely found in the biological community and distributed in various mammalian tissues. In the signal transduction process, the phospholipid inositol system finally completes the extracellular information delivery in a manner that activates PKC and Ca 2+ mobilization. Due to the wide range of extracellular signals mediated by the phospholipid inositol system, PKC and physiological processes such as synergism and desensitization of receptors and cell differentiation and proliferation,