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BACKGROUND:Early assessment of the severity of acute pancreatitis is essential to the proper management of the disease.It is dependent on the criteria of the Atlanta classification system.DATA SOURCES:PubMed search of recent relevant articles was performed to identify information about the severity and prognosis of acute pancreatitis.RESULTS:The scoring systems included the Ranson’s or Glasgow’s criteria ≥3,the APACHE II classification system ≥8,and the Balthazar’s criteria ≥4 according to the computed tomography enhanced scanning findings.The single factors on admission included age >65 years,obesity,hemoconcentration(>44%),abnormal chest X-ray,creatinine >2 mg/dl,C-reactive protein>150 mg/dl,procalcitonin >1.8 ng/ml,albumin <2.5 mg/dl,calcium <8.5 mg/dl,early hyperglycemia,increased intra-abdominal pressure,macrophage migration inhibitory factor,or a combination of IL-10 >50 pg/ml with calcium <6.6 mg/dl.CONCLUSION:The prediction of the severity of acute pancreatitis is largely based on well defined multiple factor scoring systems as well as several single risk factors.
BACKGROUND: Early assessment of the severity of acute pancreatitis is essential to the proper management of the disease. It is dependent on the criteria of the Atlanta classification system. DATA SOURCES: PubMed search of recent relevant articles was performed to identify information about the severity and prognosis of acute pancreatitis .RESULTS: The scoring systems included the Ranson’s or Glasgow’s criteria ≥3, the APACHE II classification system ≥8, and the Balthazar’s criteria ≥4 according to the computed tomography enhanced scanning findings. Single Factors on admission included age> 65 years, obesity, hemoconcentration (> 44%), abnormal chest X-ray, creatinine> 2 mg / dl, C-reactive protein> 150 mg / dl, procalcitonin> 1.8 ng / <8.5 mg / dl, early hyperglycemia, increased intra-abdominal pressure, macrophage migration inhibitory factor, or a combination of IL-10> 50 pg / ml with calcium <6.6 mg / dl.CONCLUSION: The prediction of the severity of acute pancreatitis is largely based on well defined multiple factor scoring systems as well as several single risk factors.