原发性肺癌是我国最常见的恶性肿瘤之一。近半个世纪以来,肺癌的发病率和病死率呈迅速上升趋势,到20世纪末,肺癌已成为致死率最高的恶性肿瘤。非小细胞肺癌占所有肺癌的85%以上。非小细胞肺癌的浸润和转移是一个多阶段、多步骤、多种成分参与的序贯连续过程,在此过 Primary lung cancer is one of the most common malignant tumors in our country. Nearly half a century, the incidence of lung cancer and mortality showed a rapid upward trend, by the end of the 20th century, lung cancer has become the highest lethal rate of malignant tumors. Non-small cell lung cancer accounts for more than 85% of all lung cancers. Invasion and metastasis of non-small cell lung cancer is a sequential, multi-step, multi-step sequential procedure involving multiple components