论文部分内容阅读
目的研究慢性心力衰竭(心衰)中贫血的患病情况及贫血与心功能的关系。方法183例慢性心衰患者通过临床、实验室评价和心脏超声心动图检查,参照NYHA分级,心功能Ⅰ~Ⅱ级(轻中度心衰组)86例,Ⅲ~Ⅳ级(重度心衰组)97例。比较2组的左室射血分数、左室舒张末期内径、血液学参数、患贫血率和病死率。结果183例慢性心衰患者中贫血(血红蛋白<120g/L)者43例(24.0%),重度心衰组中贫血患者(30.0%)明显多于轻中度心衰组(16.0%),P<0.05。平均随访17个月,轻中度心衰组死亡4例(5.0%),重度心衰组死亡18例(19.0%),2组相比差异有统计学意义(P<0.01)。贫血患者与非贫血患者相比病死率更高,分别为23.0%和9.0%,P<0.01。结论慢性心衰患者常伴有贫血,贫血的程度与心衰的严重程度有关,贫血使心衰患者死亡的危险性增高。
Objective To study the prevalence of anemia in chronic heart failure (CHF) and the relationship between anemia and cardiac function. Methods A total of 183 patients with chronic heart failure underwent clinical, laboratory and echocardiographic examinations. NYHA classification, 86 patients with grade Ⅰ ~ Ⅱ heart failure (mild to moderate heart failure), Ⅲ ~ Ⅳ (severe heart failure group) ) 97 cases. Left ventricular ejection fraction, left ventricular end-diastolic diameter, hematological parameters, anemia and mortality were compared between the two groups. Results Among the 183 patients with chronic heart failure, 43 (24.0%) patients had anemia (hemoglobin <120g / L), and those with severe heart failure (30.0%) had significantly more anemia than those with mild to moderate heart failure (16.0%). P <0.05. The average follow-up was 17 months. There were 4 deaths (5.0%) in mild to moderate heart failure group and 18 (19.0%) deaths in severe heart failure group. There was significant difference between the two groups (P <0.01). Patients with anemia had a higher case-fatality rate than non-anemic patients, with 23.0% and 9.0%, respectively, P <0.01. Conclusion Patients with chronic heart failure often have anemia. The degree of anemia is related to the severity of heart failure. Anemia increases the risk of death from heart failure.