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目的:实验观察蓝布正促进大脑供血供氧、止血、耐眩晕作用。方法:将小鼠分为空白对照组、蓝布正组(10.0g/kg、5.0g/kg、2.5g/kg)、天保宁组(0.01g/kg)进行断头后张口喘气实验、耐常压缺氧实验;将大鼠分为空白对照组、蓝布正组(7.00g/kg、3.50g/kg、1.75g/kg)、天保宁组(0.007g/kg),双侧颈总动脉结扎后测量大脑含水量;将豚鼠分为空白对照组、蓝布正组(5.00g/kg、2.50g/kg、1.25g/kg)、氟桂利嗪组(0.008g/kg),进行氯仿致眩晕实验;将小鼠分为空白对照组、蓝布正组(10.0g/kg、5.0g/kg、2.5g/kg)、氟桂利嗪组(0.002g/kg),经机械致眩晕后进行水迷宫测试;将小鼠分为空白对照组、蓝布正组(10.0g/kg、5.0g/kg、2.5g/kg)、云南白药组(0.2g/kg),完成止血试验。结果:蓝布正组(10.0g/kg)在断头后张口喘气试验和耐常压缺氧试验中具有显著差异;蓝布正组(7.00g/kg、3.50g/kg、1.75g/kg)及天保宁组(0.007g/kg)在双侧颈总动脉结扎后具有不同程度减轻由缺血引起的脑水肿作用;蓝布正组(5.00g/kg、2.50g/kg、1.25g/kg)和氟桂利嗪组(0.008g/kg)在对氯仿致眩晕实验中都具有程度不同的耐受作用;蓝布正组(5.0g/kg)在机械致眩晕后进行水迷宫测试中有显著差异;蓝布正组(10.0g/kg、5.0g/kg、2.5g/kg)和云南白药组(0.2g/kg)在出血后止血方面有一定的止血作用,止血效果因出血部位的不同而存在差异。结论:蓝布正有改善对大脑供血供氧及止血耐眩晕的作用。
OBJECTIVE: The experimental observation of the blue cloth is to promote the cerebral blood supply oxygen, hemostasis, vertigo resistance. Methods: The mice were divided into blank control group, blue cloth positive group (10.0g / kg, 5.0g / kg, 2.5g / kg) and Tianbaoning group (0.01g / kg) The rats were divided into blank control group, RABB group (7.00g / kg, 3.50g / kg, 1.75g / kg), Tianbaoning group (0.007g / kg) The guinea pigs were divided into blank control group, blue cloth positive group (5.00g / kg, 2.50g / kg, 1.25g / kg) and flunarizine group (0.008g / kg) The rats were divided into blank control group, blue cloth positive group (10.0g / kg, 5.0g / kg, 2.5g / kg) and flunarizine group (0.002g / kg) The rats were divided into blank control group, blue cloth positive group (10.0g / kg, 5.0g / kg, 2.5g / kg) and Yunnan Baiyao group (0.2g / kg) to complete the hemostatic test . Results: There was a significant difference between Lanbbuzheng group (10.0g / kg) and post-decapitation mouth-opening gasping test ) And Tianbaoning group (0.007g / kg) had different degrees of cerebral edema induced by ischemia after ligation of bilateral common carotid artery; kg) and flunarizine (0.008 g / kg) had varying degrees of tolerance in the chloroform-induced dizziness test; the Blueburst group (5.0 g / kg) was subjected to a water maze test after mechanical dizziness (10.0g / kg, 5.0g / kg, 2.5g / kg) and Yunnan Baiyao group (0.2g / kg) had certain hemostatic effect after hemorrhage, the effect of hemostasis due to bleeding site There are differences between the different. Conclusion: Blue cloth is to improve the cerebral blood supply of oxygen and stop bleeding vertigo effect.