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目的研究早期乳腺癌保乳术后适形调强放疗的近期疗效及并发症。方法 2007年1月—2010年1月河南省肿瘤医院收治的46例接受过标准保乳手术的早期乳腺癌患者,均为女性,年龄31~50岁,平均34.6岁,进行了适形调强放射治疗,平均随访13个月。结果全部病例无局部复发,无放射性肺炎、肺纤维化的发生。患侧乳房的大小、形状、弹性、乳头和皮肤的感觉与健侧相比,无明显差别。15例患者射野区皮肤出现2度放射性皮肤反应,5例出现腋窝皮肤3度放射反应。结论对早期乳腺癌患者进行三维适形调强放射治疗,达到了提高患者的生存质量,提高肿瘤控制率的目的 。
Objective To study the short-term effects and complications of conformal IMRT after breast-conserving surgery in early breast cancer. Methods From January 2007 to January 2010, 46 cases of early breast cancer who underwent standard breast-conserving surgery admitted to Cancer Hospital of Henan Province were female, aged 31-50 years with an average of 34.6 years old, Radiotherapy was followed up for an average of 13 months. Results All cases no local recurrence, no radiation pneumonitis, pulmonary fibrosis. Ipsilateral breast size, shape, elasticity, nipple and skin feel compared with the contralateral, no significant difference. Radiofrequency skin reactions were observed in the skin of 15 patients in the radiotherapy area and in the 5 patients. Conclusion Three-dimensional conformal IMRT in patients with early-stage breast cancer has achieved the goal of improving the quality of life and improving the rate of tumor control.