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目的探讨肝癌患者血清脂质水平改变的临床意义。方法将河南省南阳市第一人民医院近几年肝病住院患者中已确诊为肝癌的患者中69例做了血清甘油三脂(TG)、胆固醇(TCh)、高密度脂蛋白胆固醇(HDL-C)、低密度脂蛋白胆固醇(LDL)、载脂蛋白AI(ApoAI)、载脂蛋白B(ApoB)测定的患者与88例健康人员做比较分析。结果肝癌组TG、TCh、LDL和正常组有统计学差异(P<0.05),HDL-C和ApoAI、ApoB有统计学差异(P<0.01)。结论肝癌患者肝细胞损害会导致血脂代谢异常,血脂水平可反映出肝脏脂类的代谢状况,对肝病的诊断和治疗以及预后具有一定的应用价值。
Objective To investigate the clinical significance of changes in serum lipid levels in patients with liver cancer. METHODS: Serum triglyceride (TG), cholesterol (TCh), and high-density lipoprotein cholesterol (HDL-C) were detected in 69 patients with liver cancer who were diagnosed with liver cancer in Nanyang First People’s Hospital of Henan Province in recent years. ), Low-density lipoprotein cholesterol (LDL), Apolipoprotein AI (ApoAI), Apolipoprotein B (ApoB) assays were compared with 88 healthy individuals. Results There were significant differences between TG, TCh, LDL and normal group in the liver cancer group (P<0.05). There were significant differences between HDL-C, ApoAI and ApoB (P<0.01). Conclusion Hepatocellular damage in liver cancer patients will lead to abnormal lipid metabolism. Lipid levels can reflect the lipid metabolism of the liver and have a certain value in the diagnosis, treatment and prognosis of liver diseases.