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目的:分析46例肺结核并侵袭性肺部真菌感染的临床特点以及诊治效果。方法:采用回顾性方法分析,选取我院自2010年3月-2013年3月三年以来收治的46例肺结核并侵袭性肺部真菌感染患者的临床资料,对其进行分析。结果:46例肺结核并侵袭性肺部真菌感染中,分离菌株依次为33例念珠菌(71.74%)、11例霉菌(23.91%)和2例隐球菌(4.35%);其治愈、好转患者38例(82.61%),恶化患者4例(8.70%),无变化患者2例(4.35%),死亡2例(4.35%)。2例死亡患者1例并发呼吸衰竭死亡,1例糖尿病合并酮症酸中毒死亡。结论:肺结核患者容易发生侵袭性真菌感染,由于症状不具有典型性,在临床中易造成漏诊以及误诊,因此,需要结合多种手段联合诊治,提高诊治率,进而提高患者的生存质量。
Objective: To analyze the clinical features and diagnosis and treatment of 46 cases of pulmonary tuberculosis and invasive pulmonary fungal infection. Methods: A retrospective analysis of the method selected from our hospital from March 2010 - March 2013 three years since the treatment of 46 cases of pulmonary tuberculosis and invasive pulmonary fungal infection in patients with clinical data, its analysis. Results: Of the 46 cases of pulmonary tuberculosis and invasive pulmonary fungal infection, 33 were Candida (71.74%), 11 (23.91%) and 2 (4.35%). The cured and improved cases were 38 (82.61%), 4 patients (8.70%) with worsening disease, 2 patients (4.35%) with no change, and 2 deaths (4.35%). One patient died in two patients died of respiratory failure, and one patient died of diabetic ketoacidosis. CONCLUSIONS: Pulmonary tuberculosis patients are prone to invasive fungal infection. Because the symptoms are not typical, they can easily lead to missed diagnosis and misdiagnosis in clinic. Therefore, combined with a variety of means should be combined to improve the diagnosis and treatment rate and improve the quality of life of patients.