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对60例老年高血压病患者检测血清β_2-微球蛋白及血清BUN、 Cr,并以45例健康老年人作对照组。高血压病组血清β_2-微球蛋白值明显高于对照组(P<0.01)。并随高血压分期的进展血清β_2-微球蛋白值和阳性率亦随之增高。用血清β_2-微球蛋白估价老年人高血压早期肾功能损害是一项敏感、简便、可靠的方法;可作为高血压分期的一项参考指标,对指导临床用药,保护老年人肾功能有实用价值。
Serum β_2-microglobulin and serum BUN and Cr were detected in 60 elderly patients with hypertension and 45 healthy elderly controls. Serum β_2-microglobulin in hypertensive patients was significantly higher than that in the control group (P <0.01). And with the progression of hypertension, serum β_2-microglobulin value and positive rate also increased. Serum β_2-microglobulin is an sensitive, simple and reliable method to assess the early renal damage of hypertension in the elderly. It can be used as a reference index for hypertension staging to guide the clinical medication and protect the renal function of the elderly value.