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目的探讨幽门螺杆菌(HP)根除治疗消化性溃疡的临床疗效。方法 80例消化性溃疡患者,随机分为观察组和对照组,各40例。对照组采用常规三联抗HP治疗,观察组在对照组的基础上采用益生菌四联抗HP治疗,比较两组的治疗效果。结果观察组总有效率为95.0%高于对照组的80.0%,HP根除率为97.5%高于对照组的80.0%,差异有统计学意义(P<0.05)。观察组治疗后的反酸、嗳气、腹痛、腹胀评分均低于对照组,差异均有统计学意义(P<0.05)。结论四联抗HP治疗能提高消化性溃疡的治疗效果,显著缓解患者的临床症状。
Objective To investigate the clinical efficacy of Helicobacter pylori (HP) in the treatment of peptic ulcer. Methods 80 patients with peptic ulcer were randomly divided into observation group and control group, 40 cases each. The control group was treated with conventional triple anti-HP treatment. The observation group was treated with probiotics quadruple anti-HP on the basis of the control group, and the therapeutic effect was compared between the two groups. Results The total effective rate was 95.0% in the observation group and 80.0% in the control group. The HP eradication rate was 97.5% higher than that in the control group (80.0%, P <0.05). The scores of acid reflux, belching, abdominal pain and bloating after treatment in the observation group were lower than those in the control group (P <0.05). Conclusion Quadruple anti-HP treatment can improve the therapeutic effect of peptic ulcer and significantly alleviate the clinical symptoms of patients.