目的:了解重症监护病房(ICU)真菌感染的种类及其耐药特点,为使用抗真菌药物提供病原学依据。方法:收集2008-01/2008-12我院ICU患者的各部位标本,分别进行真菌培养及药物敏感试验。结果:共检出病原菌84株,其中白色念珠菌52株,占61.9%;感染最易发部位是呼吸道42例。菌株对氟康唑、伊曲康唑的耐药率分别为51.8%和62.6%。结论:白色念珠菌是ICU真菌感染的主要病原菌。 Objective: To understand the types of ICU fungal infections and their drug resistance characteristics, and to provide etiological evidence for the use of antifungal agents. Methods: The specimens of ICU patients in our hospital from January 2008 to December 2008 were collected for fungal culture and drug susceptibility tests respectively. Results: A total of 84 pathogenic bacteria were detected, of which 52 strains of Candida albicans accounted for 61.9%. The most common infection sites were respiratory tract 42 cases. The resistance rate of the strains to fluconazole and itraconazole were 51.8% and 62.6% respectively. Conclusion: Candida albicans is the main pathogen of ICU fungal infection.