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1.溴甲烷经口毒性对雄性小白鼠♂为147mg/kg,对雌性大白鼠(♀)为108mg/kg。2.熏蒸饲料中溴甲烷含量为117ppm或灌胃剂量达15mg/kg(体重),经两个月对大鼠行为、体重、食物利用率、血相(血红蛋白、红血球计数、白血球计数、白血球分类),血清谷丙转氨酶活力,(SGPT),血中非蛋白氮,肝肾重量及病理组织检查等指标均无明显影响,灌胃剂量为30mg/kg时,动物出现轻度中毒症状,60mg/kg 时,可引致死亡。大鼠对含溴甲烷饲料的最大耐受量为117ppm。3.建议粮食中溴甲烷最大允许残留量为6ppm。
1. Methyl bromide oral toxicity of male mice ♂ 147mg / kg, female rats (♀) 108mg / kg. The fumigated feed had a methyl bromide content of 117ppm or an intragastric dose of 15mg / kg (weight). The rats’ behavior, body weight, food utilization rate, blood phase (hemoglobin, erythrocyte count, leukocyte count and leukocyte classification) Serum alanine aminotransferase (SGPT), blood non-protein nitrogen, liver and kidney weight and pathological examination showed no significant effect indicators, intragastric administration of 30mg / kg, the animals showed mild symptoms of poisoning, 60mg / kg , Can cause death. The maximum toleration of rats to methyl bromide-containing feeds was 117 ppm. 3. It is recommended that the maximum allowable residual amount of methyl bromide in food be 6ppm.