量子点因具有优良的光学特性,在肿瘤早期诊断、成像和体内示踪等方面有着较好的应用前景,但其对活体及细胞的毒性作用也不容忽视。量子点能诱导细胞凋亡已经得到了公认,但其诱导细胞凋亡的分子机制尚未完全阐明。本文就国内外关于量子点诱导细胞凋亡分子机制方面的研究进行了综述。 Quantum dots have good application prospects in early diagnosis, imaging and in vivo tracing because of their excellent optical properties, but their toxic effects on living cells and cells should not be overlooked. Quantum dots can induce apoptosis has been recognized, but its molecular mechanism of apoptosis has not been fully elucidated. This review summarizes the molecular mechanisms of quantum dots in inducing apoptosis in vitro and in vivo.