The gate to metabolic crossroads

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Glycerol is a simple polyhydroxy-three-carbon compound that is highly hydrophilic and is considered a central intermediate metabolite for cellular metabolism.It is found at the crossroads among several metabolic pathways,such as glycolysis and gluco-neogenesis(for carbohydrates),lipogenesis,lipolysis,and glycero-neogenesis(for lipids),pentose-phosphate pathway(for nucleic acids),amino acid synthesis,and even energy generation by oxida-tive phosphorylation[1](Fig.1).
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