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目的探讨驻军部队军人在急性睡眠剥夺后动态血压各指标的变化。方法选择驻军某部队成建制60例健康军人进行研究,采用24 h整夜完全睡眠剥夺方法,在睡眠剥夺过程中应用动态血压记录仪监测血压各指标。结果睡眠剥夺后,(1)夜间血压负荷增高,夜间收缩压负荷为(55.3±37.0)%,夜间舒张压负荷为(26.5±28.8)%。(2)血压、心率昼夜节律消失,24 h收缩压夜间血压下降(0.5±4.8)%,24 h舒张压夜间血压下降(3.8±7.4)%,血压呈非杓型;夜间/日间心率下降率为4%,为非杓型心率。(3)日间平均心率与日间平均收缩压负荷呈正相关(r=0.269,P<0.05);夜间平均心率与夜间舒张压负荷呈正相关(r=0.338,P<0.01)。(4)血压变异性增加。结论 24 h完全性睡眠剥夺可导致健康成年男性夜间血压负荷增重,昼夜节律频率变化的消失,是发生高血压的危险因素,可能会增加心血管事件的风险。
Objective To investigate the changes of ambulatory blood pressure (BP) in military personnel of Garrison Army after acute sleep deprivation. Methods A group of garrison troops was selected to establish a system of 60 health service personnel. The sleep deprivation method was used for 24 hours and the ambulatory blood pressure recorder was used to monitor the blood pressure during sleep deprivation. Results After sleep deprivation, (1) the nocturnal blood pressure load increased, the nighttime systolic pressure load was (55.3 ± 37.0)%, and the nighttime diastolic pressure load was (26.5 ± 28.8)%. (2) The circadian rhythm of blood pressure and heart rate disappeared, the systolic blood pressure at 24 h dropped by 0.5 ± 4.8% at night, the diastolic blood pressure decreased by 24 h (3.8 ± 7.4)% at night, the blood pressure was non-dipper, and the nighttime / Rate of 4%, non-dipper heart rate. (3) The average daily heart rate was positively correlated with the average daytime systolic blood pressure (r = 0.269, P <0.05). The nighttime mean heart rate was positively correlated with nocturnal diastolic pressure (r = 0.338, P <0.01). (4) increased blood pressure variability. Conclusion 24 h sleep deprivation can lead to nocturnal increase of blood pressure load and disappearance of circadian rhythm frequency in healthy adult men. It is a risk factor for hypertension and may increase the risk of cardiovascular events.