钩端螺旋体病临床复杂、多样,对一般散发病例的确诊有赖于病原学和血清学(显微凝集试验),目前我省多数采用血清学作为诊断依据,而且多以单相血清1:400作为诊断标准。但我们在实际工作中,特别是在惯发流行区中,发现单相血清1:400作为诊断标准是存在一些问题。如何正确地应用血清学诊断钩体病?现将我们于1976年 Leptospirosis clinical complex and diverse, the diagnosis of the general distribution of cases depends on the etiology and serology (microscopic agglutination test), at present, most of our province using serology as a diagnostic basis, and more single-phase serum 1: 400 as Diagnostic criteria. However, in practical work, especially in the prevailing epidemic area, we found that there was some problem with 1: 400 monophasic serum as a diagnostic criterion. How to correctly apply serological diagnosis of leptospirosis now we in 1976