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目的:提高对术后椎间盘炎临床与影像学表现的认识,探讨其预防及介入治疗方案。材料与方法:对32 例患者椎间盘炎的病理、临床、影像学表现、预防及介入治疗方案进行分析。结果:病理学检查示间盘组织中有中性粒细胞和淋巴细胞浸润;影像学表现主要有椎间隙变窄,椎体局限性骨质破坏及终板增生与硬化;腰背部剧烈疼痛伴血沉加快是主要临床表现;主要病原菌为金黄色葡萄球菌、表皮葡萄球菌、大肠杆菌等。氯林可霉素、妥布霉素、先锋霉素V 静脉给药可渗入人体椎间盘内,手术前后用此类抗生素能阻止椎间盘炎的发生;PLD 技术可缓解症状,缩短病程。结论:手术前后应用可进入椎间盘内的抗生素是预防该病的有效方法;充分认识该病的临床与影像学表现,有助于该病的早期诊断;PLD 技术治疗该病效果好。
OBJECTIVE: To improve the understanding of clinical and radiographic findings of post-operative discitis and explore its prevention and interventional regimens. Materials and Methods: The pathological, clinical, radiological findings, prevention and interventional treatment of discitis in 32 patients were analyzed. Results: Pathological examination revealed that there was neutrophil and lymphocyte infiltration in the disc tissue. The imaging findings mainly included narrowing of the intervertebral space, limitation of vertebral bone destruction and terminal plate hyperplasia and sclerosis. Severe back pain accompanied with erythrocyte sedimentation rate Acceleration is the main clinical manifestations; the main pathogens Staphylococcus aureus, Staphylococcus epidermidis, Escherichia coli and so on. Clindamycin, tobramycin, cephalosporin V intravenous infusion can penetrate the human body disc, before and after surgery with such antibiotics can prevent the occurrence of discitis; PLD technology can relieve symptoms and shorten the course of the disease. Conclusion: The application of antibiotics into the intervertebral disc before and after operation is an effective way to prevent this disease. The full understanding of the clinical and radiological manifestations of the disease is helpful for the early diagnosis of the disease. The effect of PLD in the treatment of this disease is good.