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目的:探讨137戊型肝炎的临床特征。方法回顾性分析137例戊型病毒性肝炎患者的流行病学资料和临床特征。结果137例急性戊型肝炎患者中男女之比4.27:1;40~65岁以上者102例(74.5%);职业分布主要为农民108人(78.8%);3~5月份发病患者数为73例(53.3%);随患病年龄增加, ALB水平呈下降趋势,各组比较均有显著差异;重叠乙型肝硬化和酒精肝组的黄疸和病程明显高于单纯戊肝组。结论戊型肝炎病毒性以散发为主,主要见于成年人、男性,农村人口高发,有春季发病高峰。大多数患者预后良好,乙肝肝硬化和酒精肝基础上叠加戊肝病毒感染可能是影响患者预后的重要因素。“,”Objective To observe the clinical characteristics of patients with hepatitis E. Methods The clinical data 0f 137 patients with hepatitis E was col ected and analyzed retrospectively. Results the gender ratio of male to female was 4.27:1;the patients aged from 40 to 65-year old were the most(74.5%); the spring was the main morbidity season;the farmers was the main occupation of patients. The decreased level of ALB was associated with older age. The prevalence of jaundice and disease course in the group of hepatitis E infection accompanied by hepatitis B cirrhosis and alcohol hepatitis were higher than others. Conclusion Five epidemiological characteristics, including sporadic, adult, male, farmers and spring, are found to be associated with hepatitis E infection. The prognosis of disease in the majority of patients is favorable, and coexistence with hepatitis B cirrhosis and alcohol hepatitis can be seen as the factors which affect the prognosis.