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目的:探讨急进高原地区3种中药组方药物对人体心电图的影响,为选择有效抗缺氧药物提供依据。方法:对服用复方1号、复方2号、复方3号及安慰剂组上山前及上山后第1天、第3天、第7天、第15天心电图检查结果进行组间及服药前后对比观察。结果:进驻前后心率自身比较,除复方3号第7天、复方1号及复方3号第15天与进驻前比较无差别(P>0.05),其余进驻后与进驻前各值有显著差别(P<0.05、P<0.01);进驻后,安慰剂组与实验组比,复方3号第7天有显著差别(P<0.05);组间比,第7天复方2号与复方3号有显著差别(P<0.05)。QT/TQ进驻前后自身比较,除复方1号进驻15天与进驻前无差别(P>0.05),其余进驻后与进驻前均有显著差别(P<0.05、P<0.01);进驻后实验组与安慰剂组比较无差别(P>0.05);组间对比,复方2号与复方3号有显著差别(P<0.05)。结论:三种组方药物都有不同程度增加机体供氧、改善心肌缺血能力,但以复方3号较好。
OBJECTIVE: To investigate the effects of three traditional Chinese herbal medicines on the electrocardiogram of humans in the acute plateau area and provide evidence for the selection of effective anti-hypoxia drugs. METHODS: The electrocardiographic results of the 1st, 3rd, 7th, and 15th days after taking the Compound No. 1, Compound No. 2, Compound No. 3 and placebo groups before and after the ascent were compared between groups before and after taking the medicine. . RESULTS: There was no significant difference in the heart rate before and after the arrival, except for the compound No. 3 day 7, compound No. 1 and compound No. 3 day 15 (P>0.05), and there was a significant difference between the rest of the stay and before arrival (P>0.05). P<0.05, P<0.01); After entry, there was a significant difference between the placebo group and the experimental group on the 7th day of the compound No. 3 (P<0.05); between the groups, on the 7th day, compound No. 2 and compound No. 3 had Significant difference (P<0.05). Comparing QT/TQ before and after their arrival, except for compound No.1 stationed for 15 days, there was no significant difference before entering the station (P>0.05), and there was a significant difference between the other stations before entering and before entering the station (P<0.05, P<0.01); Compared with the placebo group, there was no difference (P>0.05); between the groups, there was a significant difference between the Compound No. 2 and the Compound No. 3 (P<0.05). Conclusion: The three prescriptions have different degrees of increase in oxygen supply to the body and improve myocardial ischemia, but the compound 3 is better.