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[目的]观察养阴活血汤联合西药治疗糖尿病合并高血压疗效。[方法]使用随机平行对照方法,将80例患者按就诊顺序编号方法简单随机分为两组。对照组40例二甲双胍,0.25g/次,2次/d,≤2g/d,餐中服用,严密监测血糖,防止低血糖反应;硝苯地平。治疗组40例养阴活血汤:白花蛇舌草25g,郁金15g,太子参、沙参、玄参、丹参各12g,桃仁、红花各7.5g,田七、牛膝各7.5g,香附、白芍、黄芪各10g,水煎250m L,1次/d,饭前30min口服;西药治疗同对照组。连续治疗30d为1疗程。观测临床症状、空腹血糖、餐后2h血糖、收缩压、舒张压、不良反应。治疗1疗程(30d),判定疗效。[结果]治疗组显效23例,有效15例,无效2例,总有效率95.00%;对照组显效15例,有效16例,无效9例,总有效率77.50%;治疗组疗效优于对照组(P<0.05)。空腹血糖治疗组明显改善(P<0.01),对照组无明显变化(P>0.05);餐后2h血糖、收缩压、舒张压两组均有改善(P<0.01),治疗组改善优于对照组(P<0.01)。[结论]养阴活血汤联合西药治疗糖尿病合并高血压,疗效满意,无严重不良反应,值得推广。
[Objective] To observe the curative effect of Yangyin Huoxue Decoction combined with Western medicine in the treatment of diabetes complicated with hypertension. [Methods] Using randomized parallel control method, 80 patients were randomly divided into two groups according to the sequence number of visiting doctor. The control group 40 metformin, 0.25g / time, 2 times / d, ≤ 2g / d, taking meals, close monitoring of blood glucose, to prevent hypoglycemic reactions; nifedipine. Treatment group, 40 cases of Yin Yang Huoxue Decoction: Hedyotis diffusa 25g, turmeric 15g, heterophylla, Radix, Scrophulariaceae, Salvia 12g, peach, saffron 7.5g, Tianqi, Achyranthes each 7.5g, incense With peony root, Astragalus each 10g, decoction 250m L, 1 time / d, 30min before meals oral; western medicine treatment with the control group. Continuous treatment of 30d for a course of treatment. Observation of clinical symptoms, fasting blood glucose, 2h postprandial blood glucose, systolic blood pressure, diastolic blood pressure, adverse reactions. Treatment of a course of treatment (30d), determine the efficacy. [Results] In the treatment group, 23 cases were markedly effective, 15 cases were effective, 2 cases were ineffective and the total effective rate was 95.00%. In the control group, 15 cases were markedly effective, 16 cases were effective, 9 cases were ineffective and the total effective rate was 77.50% (P <0.05). The fasting blood glucose treatment group was significantly improved (P <0.01), but there was no significant difference in the control group (P> 0.05); 2h postprandial blood glucose, systolic blood pressure and diastolic blood pressure were improved in both groups (P <0.01) Group (P <0.01). [Conclusion] Yangyin Huoxue decoction combined with western medicine in the treatment of diabetes complicated with hypertension has satisfactory curative effect and no serious adverse reactions and is worth popularizing.