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为了评价隆安县新生儿大规模乙肝疫苗免疫10年的流行病学效果,我们对该县1987~1996年的乙肝疫苗接种率,以及0~9岁儿童的乙型肝炎发病情况进行了调查分析。结果表明,乙肝疫苗10年全程平均接种率为88.96%,免疫后10年,0~9岁儿童的乙肝发病率为4.90/10万,较1987年同年龄组人群的乙肝发病率(33.85/10万)下降了85.52%,预防儿童乙肝发病的保护率和免疫成功率几何均数分别为87.90%和75.34%。使儿童时期乙型肝炎得到了有效地控制。
In order to evaluate the epidemiological effects of large-scale hepatitis B vaccine immunization for 10 years in Longan County, we investigated the incidence of hepatitis B vaccination and the incidence of hepatitis B in children aged 0-9 years from 1987 to 1996 in this county. The results showed that the average inoculation rate of Hepatitis B vaccine in 10 years was 88.96%. The incidence of Hepatitis B in children aged 0-9 years after immunization was 4.90 / 100 000 at 10 years after immunization. Compared with 1987, the incidence of Hepatitis B in the same age group (33.85 / 100000) decreased by 85.52%. The geometric mean of protection rate and immune success rate of prevention of childhood hepatitis B were 87.90% and 75.34% respectively. Hepatitis B in childhood has been effectively controlled.