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目的探讨置管溶栓联合腔内介入治疗在下肢动脉硬化闭塞症(ASO)患者中的应用效果。方法选取2014年2月至2016年2月大连市中心医院收治的ASO患者84例为研究对象,根据治疗方法不同分为观察组和对照组,每组42例。观察组患者接受置管溶栓联合腔内介入治疗,对照组患者接受腔内介入治疗,比较两组患者的临床治疗效果。结果观察组患者手术时间、住院时间及医疗费用,均明显低于对照组,差异均有统计学意义(均P<0.01);治疗后,观察组患者血管开通率高达97.6%,明显高于对照组的81.0%,差异有统计学意义(P<0.05)。两组患者并发症发生率比较,差异无统计学意义(P>0.05)。结论置管溶栓联合腔内介入治疗ASO效果显著,疗效确切,可作为临床首选治疗方法。
Objective To investigate the effect of catheterization and thrombolysis combined with endovascular interventional therapy in lower extremity arteriosclerosis obliterans (ASO). Methods Eighty-four ASO patients admitted from Dalian Central Hospital from February 2014 to February 2016 were selected as study subjects, and divided into observation group and control group according to different treatment methods, with 42 cases in each group. Patients in the observation group underwent catheterization and thrombolysis combined with endovascular interventional therapy, and patients in the control group received endovascular interventional therapy. The clinical effects of the two groups were compared. Results The operation time, hospitalization time and medical expenses in the observation group were significantly lower than those in the control group (all P <0.01). After treatment, the rate of vascular opening in the observation group was as high as 97.6%, significantly higher than that of the control group Group, 81.0%, the difference was statistically significant (P <0.05). There was no significant difference in complication rates between the two groups (P> 0.05). Conclusion Intra-arterial thrombolysis and endovascular interventional treatment of ASO is effective and effective, which can be used as the first choice of clinical treatment.