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为评价超短效β阻滞剂艾司洛尔(Esm-olol)对急性不稳定型心绞痛的疗效和安全性,本组对21例经常规治疗效果欠佳的顽固性心绞痛患者给予艾司洛尔治疗。在多普勒超声心动图检查后,静滴艾司洛尔使心率-血压乘积至少降低20%;当患者接受维持剂量30分钟后,重复多普勒超声心动图检查。艾司洛尔的有效浓度为17±16mg/min,其范围为8至24mg/min。该药使21例患者中的
In order to evaluate the efficacy and safety of esmolol, an ultra-short-acting beta blocker, in patients with acute unstable angina pectoris, 21 patients with refractory angina pectoris who received poor routine treatment were given esmolo Treatment. After Doppler echocardiography, intravenous esmolol reduced heart rate-pressure product by at least 20%; Doppler echocardiography was repeated when the patient received the maintenance dose for 30 minutes. The effective concentration of esmolol is 17 ± 16 mg / min, which ranges from 8 to 24 mg / min. The drug made 21 patients