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目的探讨人乳头状瘤病毒(HPV)检测、膜式液基薄层细胞学检查(TCT)联合阴道镜下活检在宫颈癌筛查中的临床意义。方法选取2010年4月~2013年4月在本院门诊就诊的2952例有性生活史并自愿进行宫颈癌筛查的患者,分别进行HPV、TCT检测和阴道镜下活检。对病理检查结果阳性的306例患者,比较HPV和TCT检测对宫颈癌前病变及宫颈癌的检出符合率。结果 HPV与TCT检出符合率比较差异无统计学意义(P>0.05);HPV、TCT检查联合阴道镜下活检的检出符合率为100%。结论 HPV、TCT检查联合阴道镜下活检有助于提高宫颈癌的检出率,早期发现癌前病变,降低病死率。
Objective To investigate the clinical significance of human papillomavirus (HPV) detection, membranous liquid-based cytology (TCT) combined with colposcopy biopsy in cervical cancer screening. Methods From April 2010 to April 2013, 2952 patients with sexual life history who volunteered for cervical cancer screening in our hospital were selected for HPV, TCT and colposcopy biopsy respectively. The positive rate of pathological examination of 306 patients, compared with HPV and TCT detection of cervical precancerous lesions and cervical cancer detection coincidence rate. Results The coincidence rate of HPV and TCT was no significant difference (P> 0.05). The coincidence rate of HPV and TCT combined with colposcopy biopsy was 100%. Conclusion HPV, TCT combined with colposcopy biopsy can help improve the detection rate of cervical cancer, early detection of precancerous lesions and reduce mortality.