Activation of human colon mast cells through proteinase activated receptor-2

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AIM:To investigate the ability of agonists of PAR-2 to stimulate release of tryptase and histamine from human colon mast cells and the potential mechanisms.METHODS:Enzymatically dispersed cells from human colons were challenged with tc-LIGRLO, tc-OLRGIL,
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AIM: TOtryptasepotentialinvestigate the ability of histamine to modulate release from human colon mast cells and the mechanisms.METHODS: Enzymatically dispersed