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目的 探讨老年恶性血液系统疾病医院感染的状况。方法 对该院 9年内收治的老年恶性血液系统疾病共 78例进行回顾性调查。结果 医院感染率为 5 0 % ,急性白血病 (AL)组感染率 (6 7.4% )明显高于非AL组(2 8.6 % ) ,常见感染部位为呼吸系统 (37% )、败血症 (2 4.1% )、口腔 (14.8% )。病原菌为革兰阳性菌 (43.3% )、真菌 (2 9.7% )和革兰阴性菌 (2 7% )。结论 老年恶性血液系统疾病医院感染发病率高 ,疾病性质、白细胞减少、住院时间长是导致医院感染的重要因素。革兰阳性球菌所致感染居首位 ,应积极采取防治措施。
Objective To investigate the status of nosocomial infections in elderly patients with hematologic malignancies. Methods A total of 78 elderly patients with malignant hematological malignancies treated within 9 years were retrospectively reviewed. Results The prevalence of nosocomial infection was 50%. The infection rate of acute leukemia (AL) group was significantly higher than that of non-AL group (22.6%). The common infection sites were respiratory system (37%), sepsis ), Oral (14.8%). The pathogenic bacteria were Gram-positive bacteria (43.3%), fungi (2 9.7%) and Gram-negative bacteria (27%). Conclusion The incidence of nosocomial hematological malignancies in hospital is high, the nature of the disease, leukopenia and long hospital stay are the major factors leading to nosocomial infection. Gram-positive cocci infection first place, should take active control measures.