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Objectives Plasma uric acid(UA) concentration was suspected to elevate in elderly with ischemic cardiomyopathy (ICM).Methods We analyzed the data of 235 elderly aged 60 years and older with coronary heart disease:silent myocardial ischemia or angina pectoris confirmed by angiography.Among these patients,154 had ICM defined as left ventricular end-diastolic diameter(LVDd) male>55 mm,female>50 mm(mean:63.51±7.70 mm) measured by echocardiography.Difference in UA was analyzed between patients with and without ICM.Results There was significant increase of UA in ICM compared with non-ICM(432.82±143.05 umol/L vs 361.06±137.35 umol/L,P<0.05 );and UA was positively related to LVDd(r=0.25,P<0.05 ).Conclusions There was significant increase of UA in elderly with ICM due to longterm silent myocardial ischemia and angina pectoris.Moreover,UA was positively related to LVDd.
Objectives Plasma uric acid (UA) concentration was suspected to elevate in elderly with ischemic cardiomyopathy (ICM). Methods We analyzed the data of 235 elderly aged 60 years and older with coronary heart disease: silent myocardial ischemia or angina pectoris confirmed by angiography. Among These patients, 154 had ICM defined as left ventricular end-diastolic diameter (LVDd) male> 55 mm, female> 50 mm (mean: 63.51 ± 7.70 mm) measured by echocardiography. Reference in UA was analyzed between patients with and without ICM. Results There was a significant increase in UA in ICM compared with non-ICM (432.82 ± 143.05 umol / L vs. 361.06 ± 137.35 umol / L, P <0.05); and UA was positively related to LVDd (r = 0.25, .Conclusions There was significant increase of UA in elderly with ICM due to longterm silent myocardial ischemia and angina pectoris. Moreover, UA was positively related to LVDd.