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目的探索冠心病(CHD)合并代谢综合征(MS)的各组成疾病及并发心脑肾血管疾病的发病情况。方法采用回顾分析法,将我院2005年1月至2006年8月收治的1201例CHD患者资料进行整理和统计。结果CHD合并MS的发病率为56.9%。CHD合并与未合并MS比较:其糖尿病(DM,85.1%、40.3%)、血脂异常(78.8%、35.1%)、超重或肥胖(71.2%、30.3%)、高血压(55.8%、27.2%)、脑梗死(12.9%、5.2%)、肾脏损害(28.3%、11.8%)的发病率比较差异有统计学意义(P<0.01);其心肌梗死(8.1%、4.1%)、脑出血(6.1%、2.5%)的发病率比较差异有统计学意义(P<0.01);其病死率(4.5%、2.1%)比较差异有统计学意义(P<0.05)。CHD合并MS的发病率随患者的病程和年龄的改变而变化。结论我地区CHD合并MS的发病率(56.9%)较其他相关报道略高。CHD合并与未合并MS比较,其DM、血脂异常、超重或肥胖、高血压、脑梗死、肾脏损害、心肌梗死、脑出血的发病率很高(P<0.01);其病死率也增高(P<0.05)。CHD合并MS的发病率随患者的病程和年龄的增加而上升。
Objective To explore the incidence of coronary heart disease (CHD) complicated with metabolic syndrome (MS) and the complication of cardiovascular and cerebrovascular diseases. Methods Using retrospective analysis, the data of 1201 CHD patients admitted to our hospital from January 2005 to August 2006 were collected and statistically analyzed. Results The incidence of CHD combined with MS was 56.9%. CHD patients with diabetes mellitus (DM, 85.1%, 40.3%), dyslipidemia (78.8%, 35.1%), overweight or obesity (71.2%, 30.3%), hypertension (55.8%, 27.2% The incidence of cerebral infarction (12.9%, 5.2%) and renal damage (28.3%, 11.8%) was significantly different between the two groups (P <0.01) %, 2.5% respectively) (P <0.01). The case fatality rate (4.5%, 2.1%) was significantly different (P <0.05). The incidence of CHD complicated with MS varies with the duration and age of the patient. Conclusion The prevalence of CHD combined with MS in our region (56.9%) is slightly higher than other related reports. The incidence of DM, dyslipidemia, overweight or obesity, hypertension, cerebral infarction, kidney damage, myocardial infarction and cerebral hemorrhage were higher in CHD patients than in those without MSD (P <0.01) <0.05). The incidence of CHD complicated with MS increased with the duration and age of the patients.