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虽然群体调查没有表明血吸虫病患者(无论是曼氏血吸虫还是日本血吸虫)有更易患病毒性乙型肝炎的风险,但已有报道认为肝脾型曼氏血吸虫病与乙型肝炎表面抗原相关。在埃及,曼氏血吸虫和病毒性肝炎是造成慢性肝病的最常见原因。越来越多的证据表明乙型肝炎合并曼氏血吸虫病患者的肝损伤比单纯乙型肝炎的肝损伤要严重得多。然而缺乏关于慢性血吸虫病人感染急性病毒性
Although population surveys do not indicate that schistosomiasis patients (both Schistosoma mansoni and Schistosoma japonicum) are at greater risk of viral hepatitis B, it has been reported that Hepatosplenic-type schistosomiasis is associated with hepatitis B surface antigen. In Egypt, Schistosoma mansoni and viral hepatitis are the most common causes of chronic liver disease. There is growing evidence that hepatitis B patients with Schistosoma mansoni have significantly more severe liver damage than hepatitis B alone. However, there is a lack of acute viral infection in patients with chronic schistosomiasis