由于现代高营养和缺少运动的生活方式,国内外肥胖及2型糖尿病(T2DM)的发病率显著上升,90%的T2DM患者伴有超重和肥胖。T2DM是多因素作用的疾病,随着病程的延长伴发各种大血管和微血管并发症,是心血管疾病、失明、肾衰、下肢截肢等的重要原因,严重影响人类的健康,所以亟需新 Due to modern high nutrition and lack of exercise-based lifestyle, the prevalence of obesity and type 2 diabetes mellitus (T2DM) has risen significantly at home and abroad, with over 90% of T2DM patients being overweight and obese. T2DM is a multifactorial disease. With the prolongation of the disease, it is associated with various macrovascular and microvascular complications. It is an important cause of cardiovascular diseases, blindness, renal failure, amputation of the lower extremities, and seriously affects human health. Therefore, it is urgently needed new